发明申请
- 专利标题： Motif-grafted hybrid polypeptides and uses thereof
- 专利标题（中）： 基质移植杂交多肽及其用途
-
申请号： US13066088申请日： 2011-04-05
-
公开(公告)号： US20110250630A1公开(公告)日： 2011-10-13
- 发明人: Dennis R. Burton , Gianluca Moroncini , R. Anthony Williamson
- 申请人： Dennis R. Burton , Gianluca Moroncini , R. Anthony Williamson
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; G01N33/68 ; C12N15/63 ; C12N5/10 ; C07K16/46 ; C07H21/04
摘要：
Provided herein are hybrid polypeptides that specifically bind to a disease-associated isoform of a polypeptide involved in diseases of protein aggregation. The hybrid polypeptides can be used for diagnosis and treatment of such diseases. In a particular embodiment, a hybrid protein that specifically binds to the infectious form of a prion (PrPSc) is provided.
信息查询
