发明申请
- 专利标题: METHOD FOR TUMOR CLASSIFICATION
- 专利标题(中): 肿瘤分类方法
-
申请号: US12736467申请日: 2009-04-10
-
公开(公告)号: US20110257025A1公开(公告)日: 2011-10-20
- 发明人: René Houtman , Robby Ruijtenbeek , Pieter Jacob Boender , Marinus Gerardus Johannes Van Beuningen , Maria Helena Hilhorst , Richard De Wijn
- 申请人: René Houtman , Robby Ruijtenbeek , Pieter Jacob Boender , Marinus Gerardus Johannes Van Beuningen , Maria Helena Hilhorst , Richard De Wijn
- 优先权: EP08154417.3 20080411
- 国际申请: PCT/EP2009/054357 WO 20090410
- 主分类号: C40B30/04
- IPC分类号: C40B30/04 ; C40B40/10
摘要:
The present invention relates to methods for identifying classification markers for tumors by monitoring the activity of protein kinases. By acquiring a phosphorylation profile of diseased and control tissue samples the method of the present invention provides classification procedures using phosphorylation patterns enabling the distinction between different types and/or sub-types of tumors. Specific classification markers for tumors can be identified enabling tumor classification, diagnosis, prognosis and/or prediction of the clinical outcome of a therapy.
信息查询