An internal combustion engine for a vehicle, such as a motorcycle, includes a crankcase, two banks of cylinders projecting from the crankcase in a 56-57 degree V-configuration, a plurality of pushrods, and a plurality of camshafts supported by the crankcase. The two banks of cylinders include a first cylinder bank that projects from the crankcase to a first cylinder head, and a second cylinder bank that projects from the crankcase to a second cylinder head. The plurality of intake and exhaust valve pushrods extend between the crankcase and the first and second cylinder heads, driven by one intake camshaft and two exhaust camshafts.