发明申请
- 专利标题: DIHYDROINDOLINONE DERIVATIVES
- 专利标题(中): 二氢吲哚啉酮衍生物
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申请号: US12994442申请日: 2009-05-25
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公开(公告)号: US20110275671A1公开(公告)日: 2011-11-10
- 发明人: Zhedong Yuan , Xiaomin Zhang , Hubo Wang , Xueyan Zhu , Hongjiang Xu , Hui Fu , Wei Song
- 申请人: Zhedong Yuan , Xiaomin Zhang , Hubo Wang , Xueyan Zhu , Hongjiang Xu , Hui Fu , Wei Song
- 申请人地址: CN Shanghai
- 专利权人: Shanghai Institute of Pharmaceutical Indusrty
- 当前专利权人: Shanghai Institute of Pharmaceutical Indusrty
- 当前专利权人地址: CN Shanghai
- 优先权: CN20810098055.5 20080523
- 国际申请: PCT/CN09/71967 WO 20090525
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; A61K31/404 ; C07D401/14 ; C07D403/06 ; A61P43/00 ; A61P1/16 ; A61P11/00 ; A61P1/18 ; A61P17/00 ; A61P13/12 ; C07D403/14 ; A61P35/00
摘要:
Disclosed are dihydroindolone compounds which can modulate the activity of protein tyrosine kinases, a method for preparing the same, and pharmaceutical compositions comprising the same. Also disclosed are use of such compounds and pharmaceutical compositions thereof in the treatment and/or prophylaxis of protein tyrosine kinase associated diseases in an organism, particularly in the treatment and/or prophylaxis of tumors and fibroblast proliferation associated diseases.
公开/授权文献
- US08829039B2 Dihydroindolinone derivatives 公开/授权日:2014-09-09
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