发明申请
- 专利标题： DIAGNOSTIC SEQUENCING WITH SMALL NUCLEIC ACID CIRCLES
- 专利标题（中）： 具有小核酸循环的诊断测序
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申请号： US13019220申请日： 2011-02-01
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公开(公告)号： US20110281768A1公开(公告)日： 2011-11-17
- 发明人: Kevin Travers , Geoff Otto , Stephen Turner , Cheryl Heiner , Congcong Ma
- 申请人： Kevin Travers , Geoff Otto , Stephen Turner , Cheryl Heiner , Congcong Ma
- 申请人地址： US CA Menlo Park
- 专利权人： Pacific Biosciences of California, Inc.
- 当前专利权人： Pacific Biosciences of California, Inc.
- 当前专利权人地址： US CA Menlo Park
- 主分类号： C40B40/06
- IPC分类号： C40B40/06 ; C40B60/12 ; C12Q1/68
摘要：
Methods, substrates, and systems for diagnostic sequencing are provided. Small circles of nucleic acids from about 10 bases to about 200 bases can be sequenced, for example using template dependent sequencing by synthesis. The use of small circles of nucleic acids allows for repeated sequencing of the same portions of the nucleic acid, providing for higher accuracy sequence determinations.
公开/授权文献
- US08309330B2 Diagnostic sequencing with small nucleic acid circles 公开/授权日：2012-11-13
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