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发明申请
US20110282328A1 Intraocular Drug Delivery Device and Associated Methods 有权
眼内药物输送装置及相关方法

Intraocular Drug Delivery Device and Associated Methods
摘要：
The present invention provides devices, systems, and methods for delivery of an active agent into the eye of a subject. In one aspect, for example, an ocular active agent delivery device (10) can include an active agent reservoir (14) disposed in an annular housing (12), the annular housing (12) being configured to fit inside of a lens capsule and at least partially encircling a line of sight of an intraocular lens within the lens capsule. The device (10) can further include a semipermeable membrane (16) operatively coupled to the active agent reservoir (14), where the semipermeable membrane (16) is configured to allow diffusion of an active agent from the active agent reservoir (14). Additionally, a valve (18) can be operatively coupled to the active agent reservoir (14), where the valve (18) is configured to allow filling of the active agent reservoir (14) with an active agent.
摘要（中）：

本发明提供了将活性剂递送到受试者的眼睛中的装置，系统和方法。 在一个方面，例如，眼部活性剂递送装置（10）可以包括设置在环形壳体（12）中的活性剂储存器（14），所述环形壳体（12）被配置成装配在透镜囊内部， 至少部分地包围晶状体囊内的眼内透镜的视线。 装置（10）还可以包括可操作地耦合到活性剂储存器（14）的半透膜（16），其中半透膜（16）构造成允许活性剂从活性剂储存器（14）扩散。 此外，阀（18）可以可操作地联接到活性剂储存器（14），其中阀（18）构造成允许用活性剂填充活性剂储存器（14）。

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