发明申请
- 专利标题： BI-SPECIFIC FUSION PROTEINS
- 专利标题（中）： 双特异融合蛋白
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申请号： US13112907申请日： 2011-05-20
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公开(公告)号： US20110286976A1公开(公告)日： 2011-11-24
- 发明人: ULRIK NIELSEN , THOMAS WICKHAM , BIRGIT SCHOEBERL , BRIAN HARMS , BRYAN LINGGI , MATTHEW ONSUM , BYRON DELABARRE
- 申请人： ULRIK NIELSEN , THOMAS WICKHAM , BIRGIT SCHOEBERL , BRIAN HARMS , BRYAN LINGGI , MATTHEW ONSUM , BYRON DELABARRE
- 申请人地址： US MA CAMBRIDGE
- 专利权人： MERRIMACK PHARMACEUTICALS
- 当前专利权人： MERRIMACK PHARMACEUTICALS
- 当前专利权人地址： US MA CAMBRIDGE
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07H21/04 ; A61K35/12 ; C07K19/00 ; A61P9/00
摘要：
Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair damaged tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to an ischemia-associated molecule; and (b) an activator domain that that detectably modulates the activity of a cellular network.
公开/授权文献
- US08691771B2 Bi-specific fusion proteins for tissue repair 公开/授权日：2014-04-08
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