- 专利标题： CHRONOTHERAPEUTIC PHARMACEUTICAL COMPOSITION
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申请号： US13145765申请日： 2010-01-21
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公开(公告)号： US20110287091A1公开(公告)日： 2011-11-24
- 发明人: Sanjay Boldhane , Shripad Jathar , Maneesh Nerurkar
- 申请人： Sanjay Boldhane , Shripad Jathar , Maneesh Nerurkar
- 申请人地址： IN Chembur
- 专利权人： Abbot Healthcare Private Limited
- 当前专利权人： Abbot Healthcare Private Limited
- 当前专利权人地址： IN Chembur
- 优先权： IN140/MUM/2009 20090122
- 国际申请： PCT/IN10/00035 WO 20100121
- 主分类号： A61K9/48
- IPC分类号： A61K9/48 ; A61K9/00 ; A61K9/28 ; A61P1/04 ; A61K31/192 ; A61P29/00 ; A61P9/10 ; A61P9/12 ; B29C43/02 ; A61K9/16
摘要：
The present invention relates to chronotherapeutic pharmaceutical compositions and a method of preparing the same. The composition comprises of at least one active ingredient, a pH independent agent and a hydrophilic agent. The active ingredient in the composition is coated with the pH independent agent. The composition provides a dual controlled release system, which aids in an initial lag time of 4-6 hours and controlled release of the active ingredient up to 24 hours.