发明申请
- 专利标题: ORAL FILM-FORM BASE AND ORAL FILM-FORM PREPARATION
- 专利标题(中): 口腔膜形式和口腔膜形成准备
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申请号: US13146829申请日: 2009-03-06
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公开(公告)号: US20110293673A1公开(公告)日: 2011-12-01
- 发明人: Daisuke Asari , Mitsuhiko Hori , Keiko Ogawa
- 申请人: Daisuke Asari , Mitsuhiko Hori , Keiko Ogawa
- 申请人地址: JP Ibaraki-shi, Osaka
- 专利权人: NITTO DENKO CORPORATION
- 当前专利权人: NITTO DENKO CORPORATION
- 当前专利权人地址: JP Ibaraki-shi, Osaka
- 优先权: JPPCT/JP2009/051511 20090129
- 国际申请: PCT/JP2009/054335 WO 20090306
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61P25/06 ; A61K31/135 ; A61P37/08 ; A61K31/18 ; A61P13/08 ; A61P1/08 ; A61K31/437 ; A61K31/426 ; A61P1/04 ; A61K31/4184 ; A61P9/12 ; A61K31/4439 ; A61P3/10 ; A61K31/4418 ; A61K31/445 ; A61K31/422
摘要:
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a drug. The base is produced by dispersing, in an organic solvent having a solubility parameter of 9.7 or higher, an edible polymer soluble in water and the organic solvent, and particles of one or two or more compounds selected from the group consisting of mono- to hexasaccharide sugars and sugar alcohols thereof which have an average particle size of 0.1 μm to 60 μm and are insoluble in an organic solvent. The present invention can therefore provide oral film-form base and preparation which have a rapid dissolution profile in the mouth and sufficient film strength, and provide a reduced sticky sensation attributed to the water-soluble polymer in the mouth and an improved feel when handled with the fingers.
公开/授权文献
- US09289386B2 Oral film-form base and oral film-form preparation 公开/授权日:2016-03-22
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