发明申请
US20110295039A1 PROCESS FOR PREPARING TOLUENEDIAMINE BY HYDROGENATION OF DINITROTOLUENE
有权
通过氢化西妥昔单抗制备托洛西胺的方法
- 专利标题: PROCESS FOR PREPARING TOLUENEDIAMINE BY HYDROGENATION OF DINITROTOLUENE
- 专利标题(中): 通过氢化西妥昔单抗制备托洛西胺的方法
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申请号: US13109399申请日: 2011-05-17
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公开(公告)号: US20110295039A1公开(公告)日: 2011-12-01
- 发明人: Andreas Raichle , Joana Coelho Tsou , Samuel Neto , Ulrich Penzel , Steffen Oehlenschläger , Michael Zöllinger , Holgar Braunsberg , Stefanie Haase , Johannes Büttner
- 申请人: Andreas Raichle , Joana Coelho Tsou , Samuel Neto , Ulrich Penzel , Steffen Oehlenschläger , Michael Zöllinger , Holgar Braunsberg , Stefanie Haase , Johannes Büttner
- 申请人地址: DE Ludwigshafen
- 专利权人: BASF SE
- 当前专利权人: BASF SE
- 当前专利权人地址: DE Ludwigshafen
- 主分类号: C07C209/36
- IPC分类号: C07C209/36
摘要:
The invention relates to a process for the continuous preparation of toluenediamine by liquid-phase hydrogenation of dinitrotoluene by means of hydrogen in the presence of a suspended, nickel-comprising catalyst in a reactor with a product isolation unit downstream of the reactor to give a product output from the reactor comprising a liquid phase comprising toluenediamine and dinitrotoluene, in which the nickel-comprising catalyst is suspended, wherein the concentration of dinitrotoluene in the liquid phase of the product output from the reactor in the region between the reactor and the downstream product isolation unit is set to a value in the range from 1 to 200 ppm by weight, based on the total weight of the liquid phase of the product output from the reactor.
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