发明申请
US20110306587A1 UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS
有权
不饱和氮杂环化合物作为PDE10抑制剂有用
- 专利标题: UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS
- 专利标题(中): 不饱和氮杂环化合物作为PDE10抑制剂有用
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申请号: US13105860申请日: 2011-05-11
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公开(公告)号: US20110306587A1公开(公告)日: 2011-12-15
- 发明人: Jennifer R. ALLEN , Jian J. Chen , Michael J. Frohn , Essa Hu , Qingyian Liu , Alexander J. Pickrell , Shannon Rumfelt , Robert M. Rzasa , Wenge Zhong
- 申请人: Jennifer R. ALLEN , Jian J. Chen , Michael J. Frohn , Essa Hu , Qingyian Liu , Alexander J. Pickrell , Shannon Rumfelt , Robert M. Rzasa , Wenge Zhong
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/497 ; C07D417/14 ; A61K31/4545 ; C07D413/14 ; C07D409/14 ; C07D491/107 ; C07D487/10 ; C07D405/14 ; A61P25/16 ; A61P25/18 ; A61P25/00 ; A61P25/28 ; A61P25/30 ; A61P25/24 ; A61P3/04 ; A61P25/14 ; C07D401/14
摘要:
Unsaturated nitrogen heterocyclic compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, Huntington's Disease, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
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