发明申请
- 专利标题： GAMMA SECRETASE MODULATORS
- 专利标题（中）： GAMMA秘密调节器
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申请号： US13128316申请日： 2009-11-11
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公开(公告)号： US20110306593A1公开(公告)日： 2011-12-15
- 发明人: Zhaoning Zhu , William J. Greenlee , Hongmei Li , Monica L. Vicarel , Jun Qin , Pawan Kumar Dhondi , Xianhai Huang , Anandan Palani , Xiaoxiang Liu , Zhong-Yue Sun , Hubert B. Josien , Ruo Xu , David James Cole , Duane A. Burnett , Chad E. Bennett , Troy McCracken , Malcolm MacCoss
- 申请人： Zhaoning Zhu , William J. Greenlee , Hongmei Li , Monica L. Vicarel , Jun Qin , Pawan Kumar Dhondi , Xianhai Huang , Anandan Palani , Xiaoxiang Liu , Zhong-Yue Sun , Hubert B. Josien , Ruo Xu , David James Cole , Duane A. Burnett , Chad E. Bennett , Troy McCracken , Malcolm MacCoss
- 国际申请： PCT/US09/63993 WO 20091111
- 主分类号： A61K31/553
- IPC分类号： A61K31/553 ; C07D498/10 ; C07D498/04 ; A61P25/28 ; C07D413/14 ; C07D498/14 ; A61K31/5395 ; C07D498/20 ; C07D413/10
摘要：
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compostions.
公开/授权文献
- US08809318B2 Gamma secretase modulators 公开/授权日：2014-08-19