- 专利标题： TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
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申请号： US13229178申请日： 2011-09-09
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公开(公告)号： US20110319447A1公开(公告)日： 2011-12-29
- 发明人: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人： Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： US MA Lexington
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D413/14 ; A61P35/00 ; A61K31/4196 ; A61K31/422 ; C07D403/12 ; C07D403/14
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US08415377B2 Triazole compounds that modulate HSP90 activity 公开/授权日：2013-04-09
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