A device for eliminating standby power consumption of an electronic appliance with a system capable of automatic power-off is provided, which includes: a power-on signal wireless transmitting unit; a control unit; a wireless signal receiving unit, connected to the control unit; a controlled electronic appliance power supply switch unit, connected to the control unit, the power supply unit, the external power source and a power input end of a controlled electronic appliance; a power supply unit of the device, connected to the control unit, the controlled electronic appliance power supply switch unit and the external power source. In the device for eliminating standby power consumption of an electronic appliance with a system capable of automatic power-off, a flexible button capable of being adhered to a surface of a switch button of a different electronic appliance is used, so the electronic appliance can be powered on by pressing the button only once like a normal operation. Meanwhile, a standby current value of the controlled electronic appliance can be detected and memorized, thereby avoiding that the standby electronic appliance or normally working electronic appliance might be unable to be turned off due to different standby power consumption of different electronic appliances.