发明申请
- 专利标题： METHODS FOR DETERMINING FRACTION OF FETAL NUCLEIC ACIDS IN MATERNAL SAMPLES
- 专利标题（中）： 用于确定母体核酸分离物的方法
-
申请号： US12958347申请日： 2010-12-01
-
公开(公告)号： US20120010085A1公开(公告)日： 2012-01-12
- 发明人: Richard P. RAVA , Yue-Jen CHUU , Manjula CHINNAPPA , David A. COMSTOCK , Gabrielle HEILEK , Michael HUNKAPILLER
- 申请人： Richard P. RAVA , Yue-Jen CHUU , Manjula CHINNAPPA , David A. COMSTOCK , Gabrielle HEILEK , Michael HUNKAPILLER
- 主分类号： C40B20/00
- IPC分类号： C40B20/00 ; C07H21/00 ; C40B30/00
摘要：
The invention provides compositions and methods for determining the fraction of fetal nucleic acids in a maternal sample comprising a mixture of fetal and maternal nucleic acids. The fraction of fetal nucleic acids can be used in determining the presence or absence of fetal aneuploidy.