Invention Application
- Patent Title: HETEROBICYCLIC METALLOPROTEASE INHIBITORS
- Patent Title (中): 异源环氧化酶抑制剂
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Application No.: US13163457Application Date: 2011-06-17
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Publication No.: US20120015920A1Publication Date: 2012-01-19
- Inventor: Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochgürtel , Michael Essers , Joshua van Veldhuizen , Bert Nolte , Brian M. Gallagher, JR. , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur G. Taveras
- Applicant: Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochgürtel , Michael Essers , Joshua van Veldhuizen , Bert Nolte , Brian M. Gallagher, JR. , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur G. Taveras
- Applicant Address: US MA Cambridge
- Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61K31/519 ; A61K31/538 ; A61P29/00 ; A61P19/02 ; A61P35/00 ; A61P9/10 ; A61P11/00 ; A61P25/00 ; A61P27/02 ; A61P31/04 ; A61P7/02 ; A61P25/16 ; A61P25/28 ; A61P31/18 ; C12N9/99 ; C07D487/04
Abstract:
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
Public/Granted literature
- US08835441B2 Heterobicyclic metalloprotease inhibitors Public/Granted day:2014-09-16
Information query
