发明申请
US20120015962A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
审中-公开
吡咯并[1,5a]吡嗪衍生物作为IRAK4调节剂
![PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS](/docs/US/2012-01-19/US20120015962A1/abs.jpg.600x600.jpg)
- 专利标题： PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
- 专利标题（中）： 吡咯并[1,5a]吡嗪衍生物作为IRAK4调节剂
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申请号： US13180589申请日： 2011-07-12
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公开(公告)号： US20120015962A1公开(公告)日： 2012-01-19
- 发明人: Nidhi Arora , Shaoqing Chen , Johannes Cornelius Hermann , Adreas Kuglstatter , Sharada Shenvi Labadie , Clara Jeou Jen Lin , Matthew C. Lucas , Amy Geraldine Moore , Eva Papp , Francisco Xavier Talamas , Jutta Wanner , Yansheng Zhai
- 申请人： Nidhi Arora , Shaoqing Chen , Johannes Cornelius Hermann , Adreas Kuglstatter , Sharada Shenvi Labadie , Clara Jeou Jen Lin , Matthew C. Lucas , Amy Geraldine Moore , Eva Papp , Francisco Xavier Talamas , Jutta Wanner , Yansheng Zhai
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; C07D495/04 ; A61P19/02 ; A61P11/00 ; A61P11/06 ; A61P11/08 ; C07D487/04 ; A61K31/4365
![PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS](/abs-image/US/2012/01/19/US20120015962A1/abs.jpg.150x150.jpg)
摘要：
Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.
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