发明申请
US20120015994A1 (2,5-DIOXOIMIDAZOLIDIN-I-YL)-N-HYDROXY-ACETAMIDES AS METALLOPROTEINASE INHIBITORS
失效
（2,5-DIOXOIMIDAZOLIDIN-I-YL）-N-羟基 - 乙酰胺作为金属蛋白酶抑制剂
- 专利标题： (2,5-DIOXOIMIDAZOLIDIN-I-YL)-N-HYDROXY-ACETAMIDES AS METALLOPROTEINASE INHIBITORS
- 专利标题（中）： （2,5-DIOXOIMIDAZOLIDIN-I-YL）-N-羟基 - 乙酰胺作为金属蛋白酶抑制剂
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申请号： US13222883申请日： 2011-08-31
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公开(公告)号： US20120015994A1公开(公告)日： 2012-01-19
- 发明人: Hans WALLBERG , Ming-Hua Xu , Guo-Qiang Lin , Xin-Sheng Lei , Piaoyang Sun , Kevin Parkes , Tony Johnson , Bertil Samuelsson
- 申请人： Hans WALLBERG , Ming-Hua Xu , Guo-Qiang Lin , Xin-Sheng Lei , Piaoyang Sun , Kevin Parkes , Tony Johnson , Bertil Samuelsson
- 申请人地址： SE Huddinge
- 专利权人： Medivir AB
- 当前专利权人： Medivir AB
- 当前专利权人地址： SE Huddinge
- 优先权： EP05112144.0 20051214
- 主分类号： A61K31/4166
- IPC分类号： A61K31/4166 ; A61P11/06 ; A61P11/00 ; C07D233/72
摘要：
The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD).
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