发明申请
US20120020921A1 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT
有权
1'-取代的CARBA-核苷类抗生素治疗药物
- 专利标题: 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT
- 专利标题(中): 1'-取代的CARBA-核苷类抗生素治疗药物
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申请号: US13117060申请日: 2011-05-26
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公开(公告)号: US20120020921A1公开(公告)日: 2012-01-26
- 发明人: Aesop CHO , Choung U. Kim , Adrian S. Ray , Lijun Zhang
- 申请人: Aesop CHO , Choung U. Kim , Adrian S. Ray , Lijun Zhang
- 申请人地址: US CA Foster City
- 专利权人: Gilead Sciences, Inc.
- 当前专利权人: Gilead Sciences, Inc.
- 当前专利权人地址: US CA Foster City
- 主分类号: A61K38/21
- IPC分类号: A61K38/21 ; A61P31/14 ; A61K31/7056 ; C07H7/06 ; A61K31/706
摘要:
Provided are prodrugs of pyrrolo[1,2-f][1,2,4]triazin-7-yl nucleoside phosphates wherein the 1′ position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.
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