发明申请
- 专利标题： EMP2 ANTIBODIES AND THEIR THERAPEUTIC USES
- 专利标题（中）： EMP2抗体及其治疗用途
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申请号： US12682032申请日： 2008-10-08
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公开(公告)号： US20120020983A9公开(公告)日： 2012-01-26
- 发明人: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra , Kathy A. Kelly , Anna M. Wu
- 申请人： Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra , Kathy A. Kelly , Anna M. Wu
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 国际申请： PCT/US08/79244 WO 20081008
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; G01N33/53 ; A61P35/00 ; C07K16/18
摘要：
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2.
公开/授权文献
- US08318906B2 EMP2 antibodies and their therapeutic uses 公开/授权日：2012-11-27
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