Invention Application
- Patent Title: HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
- Patent Title (中): 异氟醚化合物有效用作RAF激酶抑制剂
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Application No.: US13142603Application Date: 2009-12-30
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Publication No.: US20120040951A1Publication Date: 2012-02-16
- Inventor: Claudio Chuaqui , Jennifer Cossrow , James Dowling , Bing Guan , Michael Hoemann , Alexey Ishchenko , John Howard Jones , Lori Kabigting , Gnanasambandam Kumaravel , Hairuo Peng , Noel Powell , Brian Raimundo , Hiroko Tanaka , Kurt van Vloten , Jeffrey Vessels , Zhili Xin
- Applicant: Claudio Chuaqui , Jennifer Cossrow , James Dowling , Bing Guan , Michael Hoemann , Alexey Ishchenko , John Howard Jones , Lori Kabigting , Gnanasambandam Kumaravel , Hairuo Peng , Noel Powell , Brian Raimundo , Hiroko Tanaka , Kurt van Vloten , Jeffrey Vessels , Zhili Xin
- International Application: PCT/US09/69795 WO 20091230
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K31/5377 ; C07D417/14 ; A61P35/00 ; A61P9/00 ; A61P25/28 ; A61P37/00 ; A61P37/06 ; A61P29/00 ; A61P31/12 ; A61P19/08 ; A61P1/16 ; A61P7/00 ; A61P3/10 ; C12N9/99 ; C07D471/04
Abstract:
The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
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