发明申请
- 专利标题： DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS
- 专利标题（中）： 5HT2A和D3受体的双重调节剂
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申请号： US13280523申请日： 2011-10-25
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公开(公告)号： US20120040972A1公开(公告)日： 2012-02-16
- 发明人: Luca Gobbi , Georg Jaeschke , Olivier Roche , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- 申请人： Luca Gobbi , Georg Jaeschke , Olivier Roche , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- 优先权： EP07113252.6 20070726
- 主分类号： A61K31/454
- IPC分类号： A61K31/454 ; C07D413/14 ; A61P25/18 ; C07D417/14 ; A61K31/541 ; A61K31/4545 ; C07D413/04 ; A61K31/5377
摘要：
The present invention relates to compounds of the formula (I) wherein R1, R2, X and n are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the treatment of psychotic disorders, as well as other diseases such as depression and anxiety, drug dependence, dementias and memory impairment.
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