发明申请
US20120045461A1 Compositions and Methods for Inducing an Immune Response in a Mammal and Methods of Avoiding an Immune Response to Oligonucleotide Agents Such as Short Interfering RNAs
审中-公开
用于诱导哺乳动物免疫应答的组合物和方法以及避免对诸如短干扰RNA的寡核苷酸药物的免疫应答的方法
- 专利标题： Compositions and Methods for Inducing an Immune Response in a Mammal and Methods of Avoiding an Immune Response to Oligonucleotide Agents Such as Short Interfering RNAs
- 专利标题（中）： 用于诱导哺乳动物免疫应答的组合物和方法以及避免对诸如短干扰RNA的寡核苷酸药物的免疫应答的方法
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申请号： US13179421申请日： 2011-07-08
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公开(公告)号： US20120045461A1公开(公告)日： 2012-02-23
- 发明人: Gunther Hartmann , Antonin de Fougerolles , Veit Hornung , Stefan Endres
- 申请人： Gunther Hartmann , Antonin de Fougerolles , Veit Hornung , Stefan Endres
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; A61P37/04 ; A61K39/00 ; C07H1/06 ; C07H21/02
摘要：
Tis invention provides oligonucleotide agents that modulate an immune response by stimulating IFN production and methods of using such agents for therapeutic treatments of mammals.
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