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发明申请
US20120059028A1 THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS 有权
噻吩[2,3-B]吡啶衍生物作为病毒复制抑制剂

THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS
摘要：
The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
摘要（中）：

本发明涉及具有抗病毒活性的一系列化合物，更具体地涉及HIV（人类免疫缺陷病毒）复制抑制性质。 本发明还涉及制备这些化合物的方法，以及可用于这种合成的一个或多个步骤的新型中间体。 本发明还涉及包含有效量的这些化合物作为活性成分的药物组合物。 本发明还涉及这些化合物作为药物或制备用于治疗患有病毒感染，特别是HIV感染的动物的药物的用途。 本发明还涉及通过施用治疗量的这种化合物治疗动物中的病毒感染的方法，任选地与一种或多种具有抗病毒活性的其它药物组合。

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