发明申请
US20120064560A1 FOLDING OF RECOMBINANT PROTEINS VIA CO-EXPRESSION OF ARCHAEAL CHAPERONES
审中-公开
重组蛋白通过共同表达文章的折叠
- 专利标题： FOLDING OF RECOMBINANT PROTEINS VIA CO-EXPRESSION OF ARCHAEAL CHAPERONES
- 专利标题（中）： 重组蛋白通过共同表达文章的折叠
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申请号： US12999185申请日： 2009-06-16
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公开(公告)号： US20120064560A1公开(公告)日： 2012-03-15
- 发明人: Harold E. Smith , Frank T. Robb
- 申请人： Harold E. Smith , Frank T. Robb
- 国际申请： PCT/US09/47455 WO 20090616
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C07H21/04 ; C12N1/21
摘要：
The present invention relates to recombinant protein production, and more specifically, to methods for recovery of properly folder bioactive proteins by expressing chaperone genes from extremophilic Archaea, during recombinant protein synthesis in a host cell thereby significantly improving recovery of properly folded bioactive proteins.