发明申请
US20120065098A1 METHOD OF PREDICTING CHEMOTHERAPY EFFECTIVENESS IN COLON ADENOCARCINOMA PATIENTS, USING MIR-21
审中-公开
使用MIR-21预测结肠腺癌患者的化疗有效性的方法
- 专利标题: METHOD OF PREDICTING CHEMOTHERAPY EFFECTIVENESS IN COLON ADENOCARCINOMA PATIENTS, USING MIR-21
- 专利标题(中): 使用MIR-21预测结肠腺癌患者的化疗有效性的方法
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申请号: US13296545申请日: 2011-11-15
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公开(公告)号: US20120065098A1公开(公告)日: 2012-03-15
- 发明人: Carlo M. Croce , Curtis C. Harris , Aaron J. Schetter
- 申请人: Carlo M. Croce , Curtis C. Harris , Aaron J. Schetter
- 申请人地址: US MD Rockville US OH Columbus
- 专利权人: Department of Health and Human Services,The Ohio State University Research Foundation
- 当前专利权人: Department of Health and Human Services,The Ohio State University Research Foundation
- 当前专利权人地址: US MD Rockville US OH Columbus
- 主分类号: C40B30/04
- IPC分类号: C40B30/04 ; C12Q1/68
摘要:
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
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