发明申请
- 专利标题: AMIDE COMPOUNDS
- 专利标题(中): 酰胺化合物
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申请号: US12309480申请日: 2007-07-20
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公开(公告)号: US20120065196A1公开(公告)日: 2012-03-15
- 发明人: Shuji Kitamura , Thomas Daniel Aicher , Steve Gonzales , Yvan Le Huerou , Scott Alan Pratt , Yoshihisa Nakada
- 申请人: Shuji Kitamura , Thomas Daniel Aicher , Steve Gonzales , Yvan Le Huerou , Scott Alan Pratt , Yoshihisa Nakada
- 国际申请: PCT/US07/16424 WO 20070720
- 主分类号: A61K31/541
- IPC分类号: A61K31/541 ; A61K31/454 ; A61K31/445 ; C07D401/12 ; C07D413/12 ; A61K31/4245 ; C07D513/00 ; A61K31/428 ; A61K31/497 ; C07D403/12 ; A61K31/5377 ; C07D417/12 ; A61P3/04 ; A61P3/10 ; A61P3/06 ; C07D401/06
摘要:
The present invention provides compounds represented by the formula (Ie): and the formula (If): wherein each symbol is as defined in the specification.According to the present invention, these compounds have a DGAT inhibitory activity and are useful for the prophylaxis, treatment or improvement of diseases or pathologies caused by high expression or high activation of DGAT.
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