发明申请
- 专利标题： SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS
- 专利标题（中）： 用作VEGF抑制剂的替代喹啉
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申请号： US13321602申请日： 2010-05-20
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公开(公告)号： US20120065199A1公开(公告)日： 2012-03-15
- 发明人: Johan Malm , Rune Ringom , Patrizia Caldirola , Jacob Westman
- 申请人： Johan Malm , Rune Ringom , Patrizia Caldirola , Jacob Westman
- 申请人地址： SE Solna
- 专利权人： CLANOTECH AB
- 当前专利权人： CLANOTECH AB
- 当前专利权人地址： SE Solna
- 优先权： EP09160829.9 20090520
- 国际申请： PCT/EP10/56968 WO 20100520
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D413/12 ; C07D401/12 ; A61P9/10 ; C07D405/12 ; A61P35/00 ; A61P27/02 ; A61P29/00 ; A61K31/4709 ; A61P17/06
摘要：
A compound of formula (I) as well as pharmaceutically acceptable salts thereof and pharmaceutical compositions including a therapeutically effective amount of the compounds. The compound is useful in treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema and psoriasis.
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