发明申请
- 专利标题： MORPHOLINOPURINE DERIVATIVES
- 专利标题（中）： 多环芳烃衍生物
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申请号： US13308239申请日： 2011-11-30
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公开(公告)号： US20120071476A1公开(公告)日： 2012-03-22
- 发明人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
- 申请人： Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
- 申请人地址： JP Tokyo
- 专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人地址： JP Tokyo
- 优先权： JP2008-264797 20081014; JP2009-121690 20090520
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61P35/00 ; C07D413/14
摘要：
There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
公开/授权文献
- US08309546B2 Morpholinopurine derivatives 公开/授权日：2012-11-13
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