The present invention relates to a control system and a method for a hybrid vehicle which may optimally control the operating point of a vehicle. A control method for a hybrid vehicle includes detecting driving requests and a state of charge (SOC) of a battery when the vehicle is driving in HEV mode, determining a motor operating point and an engine operating point when the battery is in low SOC state, and compensating the motor operating point and the engine operating point by applying a climbing degree of the vehicle and theatmospheric pressure.