发明申请
- 专利标题： BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS
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申请号： US13375550申请日： 2010-06-02
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公开(公告)号： US20120077794A1公开(公告)日： 2012-03-29
- 发明人: Siegfried Benjamin Christensen, IV , Donghui Qin , Shenglin Chen , Xing Huang , Di Li , Fei Li , Xiaojuan Lin , Shi Lu , Maoyun Lv , Chengde Wu , Weiliang Xu , Gang Yan , Jianxing Yuan , Weina Zhang , Zhiliu Zhang
- 申请人： Siegfried Benjamin Christensen, IV , Donghui Qin , Shenglin Chen , Xing Huang , Di Li , Fei Li , Xiaojuan Lin , Shi Lu , Maoyun Lv , Chengde Wu , Weiliang Xu , Gang Yan , Jianxing Yuan , Weina Zhang , Zhiliu Zhang
- 申请人地址： US PA Philadelphia
- 专利权人： GLAXSMITHKLINE LLC
- 当前专利权人： GLAXSMITHKLINE LLC
- 当前专利权人地址： US PA Philadelphia
- 国际申请： PCT/US10/37009 WO 20100602
- 主分类号： A61K31/444
- IPC分类号： A61K31/444 ; A61K31/496 ; A61K31/4545 ; C07D413/14 ; A61K31/5377 ; A61K31/551 ; C07D417/14 ; A61K31/541 ; A61P3/04 ; A61P3/10 ; A61P9/10 ; A61P25/24 ; A61P25/22 ; A61P25/30 ; C07D401/14
摘要：
The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and diabetes.
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