发明申请
US20120083504A1 Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof
有权
反酰胺化合物作为蛋白质脱乙酰酶抑制剂及其使用方法
- 专利标题： Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof
- 专利标题（中）： 反酰胺化合物作为蛋白质脱乙酰酶抑制剂及其使用方法
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申请号： US13310168申请日： 2011-12-02
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公开(公告)号： US20120083504A1公开(公告)日： 2012-04-05
- 发明人: John H. van Duzer , Ralph Mazitschek , Walter Ogier , James E. Bradner , Guoxiang Huang , Dejian Xie , Nan Yu
- 申请人： John H. van Duzer , Ralph Mazitschek , Walter Ogier , James E. Bradner , Guoxiang Huang , Dejian Xie , Nan Yu
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61P35/00 ; A61P19/02 ; A61P17/06 ; A61P11/00 ; A61P11/06 ; A61P19/08 ; A61P7/06 ; A61P29/00 ; A61P1/00 ; A61P33/02 ; A61P3/00 ; A61P25/16 ; A61P25/28 ; C07D239/42
摘要：
The present invention relates to novel “reverse amide” compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.