发明申请
US20120087984A1 STABILIZATION OF CHEMICAL COMPOUNDS USING NANOPARTICULATE FORMULATIONS
审中-公开
使用纳米脂肪酸配方化学化学品的稳定性
- 专利标题: STABILIZATION OF CHEMICAL COMPOUNDS USING NANOPARTICULATE FORMULATIONS
- 专利标题(中): 使用纳米脂肪酸配方化学化学品的稳定性
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申请号: US13252143申请日: 2011-10-03
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公开(公告)号: US20120087984A1公开(公告)日: 2012-04-12
- 发明人: Elaine LIVERSIDGE , Linden Wei
- 申请人: Elaine LIVERSIDGE , Linden Wei
- 专利权人: Elan Pharma International Ltd.
- 当前专利权人: Elan Pharma International Ltd.
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61P35/00 ; A61K31/337 ; C07D305/14 ; B82Y40/00 ; B82Y5/00
摘要:
Methods for stabilizing chemical compounds, particularly pharmaceutical agents, using nanoparticulate compositions are described. The nanoparticulate compositions comprise a chemical compound, such as a pharmaceutical agent, and at least one surface stabilizer. The component chemical compound exhibits chemical stability, even following prolonged storage, repeated freezing-thawing cycles, exposure to elevated temperatures, or exposure to non-physiological pH conditions.