Invention Application
- Patent Title: Methods for Increasing the Production of Ethanol from Microbial Fermentation
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Application No.: US13316963Application Date: 2011-12-12
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Publication No.: US20120094349A1Publication Date: 2012-04-19
- Inventor: James L. Gaddy , Dinesh K. Arora , Ching-Whan Ko , John Randall Phillips , Rahul Basu , Carl V. Wikstrom , Edgar C. Clausen
- Applicant: James L. Gaddy , Dinesh K. Arora , Ching-Whan Ko , John Randall Phillips , Rahul Basu , Carl V. Wikstrom , Edgar C. Clausen
- Applicant Address: US IL Lisle
- Assignee: INEOS BIO LIMITED
- Current Assignee: INEOS BIO LIMITED
- Current Assignee Address: US IL Lisle
- Main IPC: C12P7/06
- IPC: C12P7/06 ; C12P7/14

Abstract:
A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.
Public/Granted literature
- US08642302B2 Methods for increasing the production of ethanol from microbial fermentation Public/Granted day:2014-02-04
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