发明申请
- 专利标题: INHIBITORS OF FATTY ACID AMIDE HYDROLASE
- 专利标题(中): 脂肪酸酰胺水解酶抑制剂
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申请号: US13263328申请日: 2010-04-07
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公开(公告)号: US20120094957A1公开(公告)日: 2012-04-19
- 发明人: Alfredo C. Castro , Michael J. Grogan , Daniel A. Snyder
- 申请人: Alfredo C. Castro , Michael J. Grogan , Daniel A. Snyder
- 国际申请: PCT/US2010/030272 WO 20100407
- 主分类号: A61K31/69
- IPC分类号: A61K31/69 ; A61P29/00 ; A61P25/24 ; A61P25/22 ; A61P25/04 ; A61P9/00 ; A61P25/00 ; A61P19/02 ; A61P1/00 ; A61P25/06 ; C07F5/02 ; A61P27/06
摘要:
Provided herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, or mixtures thereof, wherein Z1, Z2, X1, X2, X3, R1, R2 R3, m and n are defined herein. Also provided are pharmaceutically acceptable compositions that include a compound of formula I and a pharmaceutically acceptable excipient. Also provided are methods for treating FAAH-mediated disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound or composition of the present invention.
公开/授权文献
- US08546564B2 Inhibitors of fatty acid amide hydrolase 公开/授权日:2013-10-01
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