发明申请
- 专利标题: MODIFIED NUCLEOTIDES
- 专利标题(中): 改性核酸
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申请号: US13281275申请日: 2011-10-25
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公开(公告)号: US20120095201A1公开(公告)日: 2012-04-19
- 发明人: John MILTON , Xiaolin Wu , Mark Smith , Joseph Brennan , Colin Barnes , Xiaohai Liu , Silke Ruediger
- 申请人: John MILTON , Xiaolin Wu , Mark Smith , Joseph Brennan , Colin Barnes , Xiaohai Liu , Silke Ruediger
- 申请人地址: GB Nr. Saffron Walden
- 专利权人: ILLUMINA CAMBRIDGE LIMITED
- 当前专利权人: ILLUMINA CAMBRIDGE LIMITED
- 当前专利权人地址: GB Nr. Saffron Walden
- 优先权: GB0230037.4 20021223; GB0303924.5 20030220
- 主分类号: C07H1/00
- IPC分类号: C07H1/00
摘要:
Provided herein is a method for replacing the allyl group in a compound of formula R—O-allyl, R2N(allyl), RNH(allyl), RN(allyl)2 or R—S-allyl with a hydrogen, using a transition metal and one or more phosphine ligands.
公开/授权文献
- US08597881B2 Modified nucleotides 公开/授权日:2013-12-03
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