发明申请
US20120101081A1 AMINO-PYRROLIDINE-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
有权
氨基吡咯烷酮 - 亚氨基二异氰酸酯作为单羟乙基脂肪酶抑制剂
- 专利标题: AMINO-PYRROLIDINE-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
- 专利标题(中): 氨基吡咯烷酮 - 亚氨基二异氰酸酯作为单羟乙基脂肪酶抑制剂
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申请号: US13277734申请日: 2011-10-20
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公开(公告)号: US20120101081A1公开(公告)日: 2012-04-26
- 发明人: Yue-Mei Zhang , Peter J. Connolly , Shu-Chen Lin , Mark J. MacIelag
- 申请人: Yue-Mei Zhang , Peter J. Connolly , Shu-Chen Lin , Mark J. MacIelag
- 主分类号: A61K31/4725
- IPC分类号: A61K31/4725 ; A61P25/00 ; C07D403/14 ; C07D417/14 ; C07D403/12
摘要:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula (I) as follows: wherein Y, Z, and R1, and R2 are defined herein.
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