发明申请
US20120101280A1 COMPOUND HAVING SPIRO-BONDED CYCLIC GROUP AND USE THEREOF 失效
具有螺旋结合循环组的化合物及其用途

COMPOUND HAVING SPIRO-BONDED CYCLIC GROUP AND USE THEREOF
摘要:
The invention relates to a compound represented by formula (I): a salt thereof, an N-oxide thereof, or a solvate thereof (symbols in the formula are as described in the specification).The compound of the present invention exhibits very low risk of side effects and also has persistent and strong antagonistic activity against CXCR4, and is therefore useful as pharmaceuticals, for example, preventive and/or therapeutic agent for inflammatory and immune diseases, infections (for example, HIV infection), diseases associated with HIV infection (for example, acquired immunodeficiency syndrome (AIDS)), cancer, cancer metastasis, psychoneurotic diseases and cardiovascular diseases (for example, retinopathy), metabolic diseases, cancerous diseases, or an agent for regeneration therapy.
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