发明申请
US20120114688A1 VACCINES COMPRISING NON-SPECIFIC NUCLEOSIDE HYDROLASE AND STEROL 24-C-METHYLTRANSFERASE (SMT) POLYPEPTIDES FOR THE TREATMENT AND DIAGNOSIS OF LEISHMANIASIS
审中-公开
包含非特异性核苷酸水解酶和固醇24-C-甲基衍生物（SMT）多肽的疫苗用于治疗和诊断淋巴细胞
- 专利标题： VACCINES COMPRISING NON-SPECIFIC NUCLEOSIDE HYDROLASE AND STEROL 24-C-METHYLTRANSFERASE (SMT) POLYPEPTIDES FOR THE TREATMENT AND DIAGNOSIS OF LEISHMANIASIS
- 专利标题（中）： 包含非特异性核苷酸水解酶和固醇24-C-甲基衍生物（SMT）多肽的疫苗用于治疗和诊断淋巴细胞
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申请号： US13290834申请日： 2011-11-07
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公开(公告)号： US20120114688A1公开(公告)日： 2012-05-10
- 发明人: Ajay Bhatia , Steven G. Reed
- 申请人： Ajay Bhatia , Steven G. Reed
- 申请人地址： US WA Seattle
- 专利权人： INFECTIOUS DISEASE RESEARCH INSTITUTE
- 当前专利权人： INFECTIOUS DISEASE RESEARCH INSTITUTE
- 当前专利权人地址： US WA Seattle
- 主分类号： A61K39/008
- IPC分类号： A61K39/008 ; C12N15/62 ; A61P33/02 ; C12N11/00 ; A61P37/04 ; C12N9/10 ; G01N33/569
摘要：
Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise fusion polypeptides comprising Leishmania antigens, in particular, SMT and NH antigens or immunogenic portions or variants thereof, as well as polynucleotides encoding such fusion polypeptides.
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