发明申请
- 专利标题: METHOD FOR EVALUATING CANCER
- 专利标题(中): 癌症评估方法
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申请号: US13265680申请日: 2010-04-21
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公开(公告)号: US20120115139A1公开(公告)日: 2012-05-10
- 发明人: Masahiko Kuroda , Akira Saito , Maki Sano
- 申请人: Masahiko Kuroda , Akira Saito , Maki Sano
- 申请人地址: JP Shinjuku-ku, Tokyo JP Minato-ku, Tokyo
- 专利权人: TOKYO MEDICAL UNIVERSITY,NEC CORPORATION
- 当前专利权人: TOKYO MEDICAL UNIVERSITY,NEC CORPORATION
- 当前专利权人地址: JP Shinjuku-ku, Tokyo JP Minato-ku, Tokyo
- 优先权: JP2009-103332 20090421
- 国际申请: PCT/JP2010/057102 WO 20100421
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
Provided is a cancer evaluation method using a novel cancer marker for evaluating the onset, the preclinical stage, the clinical stage, or the prognosis of a cancer in a subject. At least one miRNA selected from hsa-miR-92 and hsa-miR-494 is used as the novel cancer marker in cancer evaluation. The cancer marker in a sample of a cell or a tissue is detected, and the possibility of a cancer in the sample is evaluated based on the expression level of the cancer marker. According to this evaluation method, by detecting the miRNA as the cancer marker, it becomes possible to evaluate the possibility of a cancer in the sample with excellent reliability. As a method for detecting the cancer marker, it is preferable to perform an in situ hybridization method using a labeled probe with respect to the sample that has been immobilized, for example.