发明申请
- 专利标题： 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
- 专利标题（中）： 作为RENIN抑制剂的3,4,5-取代的哌啶
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申请号： US13349869申请日： 2012-01-13
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公开(公告)号： US20120115859A1公开(公告)日： 2012-05-10
- 发明人: Peter HEROLD , Robert Mah , Vincenzo Tschinke , Nathalie Jotterand , Dirk Behnke , Aleksandar Stojanovic , Stefan Stutz , Michael Quirmbach , Stjepan Jelakovic
- 申请人： Peter HEROLD , Robert Mah , Vincenzo Tschinke , Nathalie Jotterand , Dirk Behnke , Aleksandar Stojanovic , Stefan Stutz , Michael Quirmbach , Stjepan Jelakovic
- 优先权： CH00593/05 20050331; CH0086/06 20060119
- 主分类号： A61K31/538
- IPC分类号： A61K31/538 ; C07D413/14 ; C07D405/12 ; A61K31/453 ; A61P9/00 ; A61P9/04 ; A61P27/06 ; A61P9/10 ; A61P13/12 ; C07D413/12 ; A61P9/12
摘要：
The application relates to novel substituted piperidines of the general formula (II) in which R1′, R2′, R2″, R4′, X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.
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