发明申请
US20120115902A1 3H-Imidazo [4, 5-B] Pyridine- 6 -Carboxamides As Anti-Inflammatory Agents
失效
3H-咪唑并[4,5-B]吡啶-6-羧酰胺作为抗炎剂
![3H-Imidazo [4, 5-B] Pyridine- 6 -Carboxamides As Anti-Inflammatory Agents](/docs/US/2012-05-10/US20120115902A1/abs.jpg.600x600.jpg)
- 专利标题： 3H-Imidazo [4, 5-B] Pyridine- 6 -Carboxamides As Anti-Inflammatory Agents
- 专利标题（中）： 3H-咪唑并[4,5-B]吡啶-6-羧酰胺作为抗炎剂
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申请号： US13119836申请日： 2009-09-25
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公开(公告)号： US20120115902A1公开(公告)日： 2012-05-10
- 发明人: Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer
- 申请人： Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer
- 申请人地址： DE Ingelheim am Rhein
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址： DE Ingelheim am Rhein
- 优先权： EP08165120.0 20080925
- 国际申请： PCT/EP2009/062425 WO 20090925
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61P11/06 ; A61P11/00 ; A61P1/00 ; A61P25/00 ; A61P25/06 ; A61P31/12 ; A61P31/04 ; A61P31/10 ; A61P17/02 ; A61P35/00 ; A61P7/00 ; A61P9/10 ; A61P19/06 ; A61P19/02 ; A61P29/00 ; A61P19/04 ; A61P1/18 ; A61P13/12 ; A61P27/02 ; A61P17/06 ; A61P3/10 ; A61P25/28 ; A61P37/00 ; A61P37/08 ; A61P1/04 ; A61P19/10 ; A61P19/08 ; A61P1/02 ; A61P9/00 ; A61P17/00 ; C07D471/04
![3H-Imidazo [4, 5-B] Pyridine- 6 -Carboxamides As Anti-Inflammatory Agents](/abs-image/US/2012/05/10/US20120115902A1/abs.jpg.150x150.jpg)
摘要：
There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.
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