A system, in certain embodiments, includes a centrifugal compressor diffuser vane including a leading edge, a trailing edge, and a constant thickness section extending between the leading edge and the trailing edge. A radius of curvature of the leading edge and a radius of curvature of the trailing edge vary along a span of the vane. A ratio of a length of the constant thickness section to a chord length of the vane is at least approximately 50%, and the ratio is substantially constant along the span of the vane.