发明申请
US20120129842A1 BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
审中-公开
PRO-MATRIX金属蛋白酶激活的双嘧达莫抑制剂
- 专利标题: BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
- 专利标题(中): PRO-MATRIX金属蛋白酶激活的双嘧达莫抑制剂
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申请号: US13297400申请日: 2011-11-16
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公开(公告)号: US20120129842A1公开(公告)日: 2012-05-24
- 发明人: Paul Francis JACKSON , Brett Andrew Tounge , Kristi Anne Leonard , Yan Zhang , Aihua Wang , Michael Hawkins , Umar S.M. Maharoof , Joseph Kent Barbay
- 申请人: Paul Francis JACKSON , Brett Andrew Tounge , Kristi Anne Leonard , Yan Zhang , Aihua Wang , Michael Hawkins , Umar S.M. Maharoof , Joseph Kent Barbay
- 主分类号: A61K31/551
- IPC分类号: A61K31/551 ; C07D417/14 ; A61K31/427 ; A61K31/454 ; A61K31/496 ; A61K31/4709 ; A61K31/5377 ; A61P35/00 ; A61P19/02 ; A61P19/08 ; A61P9/00 ; A61P1/04 ; A61P9/12 ; A61P11/00 ; A61P1/00 ; A61P29/00 ; A61P17/02 ; A61P1/16 ; A61P25/00 ; A61P11/06 ; A61P13/12 ; A61P25/06 ; A61P9/10 ; C07D417/04
摘要:
This invention relates to bisthiazole I and its therapeutic and prophylactic uses, wherein the variables A, R5, R6, and R7 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.
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