发明申请
- 专利标题： Pyrazine Derivatives for Bioconjugation
- 专利标题（中）： 吡嗪衍生物用于生物共轭
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申请号： US13344930申请日： 2012-01-06
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公开(公告)号： US20120134930A1公开(公告)日： 2012-05-31
- 发明人: Raghavan Rajagopalan , Richard B. Dorshow
- 申请人： Raghavan Rajagopalan , Richard B. Dorshow
- 申请人地址： US MO Hazelwood
- 专利权人： Mallinckrodt LLC
- 当前专利权人： Mallinckrodt LLC
- 当前专利权人地址： US MO Hazelwood
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; C07D403/12 ; C07K7/08 ; C07D241/28
摘要：
Provided are compounds and compositions of general Formula IX: E1-L-Ar-X-PA, that may be utilized in bioconjugation procedures, where Ar is a chromophore and PA is a functional group capable of being attached to any bioactive molecule of interest. The present invention provides Formulas I-III that are capable of being attached to a bioactive vector for the selective delivery of said photoactive pyrazine derivatives to a desired biological target.
公开/授权文献
- US08664392B2 Pyrazine derivatives for bioconjugation 公开/授权日：2014-03-04
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