发明申请
- 专利标题: METHODS OF INHIBITING VIRAL INFECTION
- 专利标题(中): 抑制病毒感染的方法
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申请号: US12261603申请日: 2008-10-30
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公开(公告)号: US20120142731A1公开(公告)日: 2012-06-07
- 发明人: Michael Kinch , Michael Goldblatt
- 申请人: Michael Kinch , Michael Goldblatt
- 申请人地址: US MD Gaithersburg
- 专利权人: Functional Genetics, Inc.
- 当前专利权人: Functional Genetics, Inc.
- 当前专利权人地址: US MD Gaithersburg
- 主分类号: A61K31/4706
- IPC分类号: A61K31/4706 ; A61P31/12 ; C12N5/071 ; A61P31/14 ; A61P31/16 ; C07D215/46 ; A61P31/18
摘要:
Compounds, pharmaceutical compositions and methods of inhibiting viral infection in a mammal in need of same, are provided, which employ compounds of the formula wherein each X is independently H or an electrodonating group, each Y is independently H, alkyl of 1-4 carbon atoms, hydroxy, alkoxy or methylene and wherein Substituent Z is a di-or-tri akly amino, or alkyl di or tri amino, optionally substituted with a halogen moiety. This family of compounds, designated FGI-104 herein, inhibits viral infection therapeutically and prophylactically.
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