- 专利标题： Targeting Kidney Mesangium With Nanoparticles of Defined Diameter
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申请号： US13316366申请日： 2011-12-09
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公开(公告)号： US20120148488A1公开(公告)日： 2012-06-14
- 发明人: Mark E. Davis , Chung Hang J. Choi , Jonathan Zuckerman
- 申请人： Mark E. Davis , Chung Hang J. Choi , Jonathan Zuckerman
- 申请人地址： US CA Pasadena
- 专利权人： CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人： CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： US CA Pasadena
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; A61K51/02 ; A61K9/00 ; A61P13/12 ; G01N21/64 ; A61K38/02 ; C12Q1/02 ; B82Y15/00 ; B82Y5/00
摘要：
Described herein are methods of treating a disorder affecting the mesangial cells in a subject by administering an engineered nanoparticle (ENP) capable of delivering a therapeutic agent to the subject. Also provided are diagnostic methods for administering to a subject an ENP, analyzing a mesangial cell of the subject and determining whether the engineered nanoparticle is present in a mesangial cell of the subject.
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