发明申请
US20120157342A1 PREDICTIVE BIOMARKERS USEFUL FOR CANCER THERAPY MEDIATED BY A WEE1 INHIBITOR
审中-公开
预防性生物标志物有用于癌症治疗由第一个抑制剂介导
- 专利标题： PREDICTIVE BIOMARKERS USEFUL FOR CANCER THERAPY MEDIATED BY A WEE1 INHIBITOR
- 专利标题（中）： 预防性生物标志物有用于癌症治疗由第一个抑制剂介导
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申请号： US13393915申请日： 2010-08-26
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公开(公告)号： US20120157342A1公开(公告)日： 2012-06-21
- 发明人: Shinji Mizuarai , Hiraku Itadani , Kazunori Yamanaka , Toshihide Nishibata , Tsuyoshi Arai , Hiroshi Hirai , Hidehito Kotani
- 申请人： Shinji Mizuarai , Hiraku Itadani , Kazunori Yamanaka , Toshihide Nishibata , Tsuyoshi Arai , Hiroshi Hirai , Hidehito Kotani
- 国际申请： PCT/JP2010/064976 WO 20100826
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C40B30/04
摘要：
The present invention provides the identification of biomarker gene sets whose expression levels are useful for predicting a patient's response to a therapeutically effective dose of a Wee1 inhibitor as well the ability to predict said response prior to dosing with the Wee1 inhibitor. Additional uses are also disclosed in the specification.
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