发明申请
- 专利标题： RHO KINASE INHIBITORS
- 专利标题（中）： RHO激酶抑制剂
-
申请号： US13171696申请日： 2011-06-29
-
公开(公告)号： US20120165322A1公开(公告)日： 2012-06-28
- 发明人: Brian Nicholas Cook , Jennifer A. Kowalski , Xiang Li , Daniel Richard Marshall , Sabine Schlyer , Robert Sibley , Lana Louise Smith-Keenan , Fariba Soleymanzadeh , Ronald John Sorcek , Erick Richard Roush Young , Yunlong Zhang
- 申请人： Brian Nicholas Cook , Jennifer A. Kowalski , Xiang Li , Daniel Richard Marshall , Sabine Schlyer , Robert Sibley , Lana Louise Smith-Keenan , Fariba Soleymanzadeh , Ronald John Sorcek , Erick Richard Roush Young , Yunlong Zhang
- 申请人地址： DE Ingelheim am Rhein
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址： DE Ingelheim am Rhein
- 主分类号： A61K31/472
- IPC分类号： A61K31/472 ; A61K31/4725 ; C07D471/04 ; C07D487/04 ; A61K31/4985 ; C07D417/14 ; C07D417/12 ; A61K31/5415 ; A61K31/541 ; C07D413/12 ; C07D413/14 ; C07D401/12 ; A61K31/506 ; C07D405/12 ; A61K31/5377 ; A61K31/538 ; A61K31/497 ; A61K31/4439 ; C07D513/04 ; A61K31/428 ; A61P9/12 ; A61P9/10 ; A61P9/00 ; A61P25/00 ; A61P15/10 ; A61P13/12 ; A61P11/06 ; A61P27/06 ; A61P35/00 ; A61P25/28 ; A61P29/00 ; A61P17/06 ; A61P1/00 ; A61K31/437 ; C07D217/02
摘要：
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
公开/授权文献
- US08697911B2 Rho kinase inhibitors 公开/授权日：2014-04-15