发明申请
- 专利标题： SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS
- 专利标题（中）： 取代的吡唑啉衍生物作为激酶抑制剂
-
申请号： US13327979申请日： 2011-12-16
-
公开(公告)号： US20120190678A1公开(公告)日： 2012-07-26
- 发明人: Francesco Casuscelli , Claudia Piutti , Antonella Ermoli , Daniela Faiardi
- 申请人： Francesco Casuscelli , Claudia Piutti , Antonella Ermoli , Daniela Faiardi
- 优先权： EP10195675.3 20101217
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/519 ; C12N9/99 ; A61P35/00 ; A61P35/02 ; A61N5/00 ; A61P9/10 ; A61P11/00 ; A61P19/02 ; A61P29/00 ; A61P37/06 ; C07D487/04 ; A61P17/06
摘要：
The present invention relates to substituted pyrazolo[4,3-h]quinazoline compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular PIM kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.
公开/授权文献
信息查询
IPC分类:
